| Date | Opponent | Location | Outcome/Time |
| 09/01/2000 | George Mason | Fairfax, Va. (George Mason Tournament) | L, 0-3 Recap | Stats |
| 09/01/2000 | Maryland-Baltimore | Fairfax, Va. (George Mason Tournament) | L, 2-3 Recap | Stats |
| 09/02/2000 | Central Michigan | Fairfax, Va. (George Mason Tournament) | L, 1-3 Recap | Stats |
| 09/05/2000 | East Tennessee State* | Johnson City, Tenn. | L, 2-3 Recap | Stats |
| 09/08/2000 | Florida International | Orlando, Fla. (UCF Tournament) | W, 3-2 Recap | Stats |
| 09/08/2000 | Bowling Green | Orlando, Fla. (UCF Tournament) | L, 0-3 Recap | Stats |
| 09/09/2000 | Central Florida | Orlando, Fla. (UCF Tournament) | L, 1-3 Recap | Stats |
| 09/15/2000 | UNC Greensboro* | Cullowhee, N.C. | W, 3-0 Recap | Stats |
| 09/17/2000 | Davidson* | Cullowhee, N.C. | Recap | Stats |
| 09/22/2000 | Troy State | Birmingham, Ala. (Samford Tournament | L, 3-0 Recap | Stats |
| 09/23/2000 | Samford | Birmingham, Ala. (Samford Tournament) | L, 3-2 Recap | Stats |
| 09/23/2000 | Tennessee State | Birmingham, Ala. (Samford Tournament) | W, 3-0 Recap | Stats |
| 09/24/2000 | Georgia Southern* | Cullowhee, N.C. | W, 3-1 Recap | Stats |
| 09/28/2000 | Wofford* | Spartanburg, S.C. | W, 3-0 Recap | Stats |
| 10/02/2000 | Furman* | Cullowhee, N.C. | L, 3-2 Recap | Stats |
| 10/04/2000 | Appalachian State* | Boone, N.C. | W, 3-0 Recap | Stats |
| 10/07/2000 | College of Charleston* | Cullowhee, N.C. | W, 3-2 Recap | Stats |
| 10/08/2000 | The Citadel* | Cullowhee, N.C. | W, 3-0 Recap | Stats |
| 10/13/2000 | East Tennessee State* | Cullowhee, N.C. | L, 3-2 Recap | Stats |
| 10/14/2000 | Appalachian State* | Cullowhee, N.C. | L, 3-0 Recap | Stats |
| 10/18/2000 | Chattanooga* | Cullowhee, N.C. | W, 3-2 Recap | Stats |
| 10/21/2000 | UNC Greensboro* | Greensboro, N.C. | W, 3-1 Recap | Stats |
| 10/22/2000 | Davidson* | Davidson, N.C. | W, 3-2 Recap | Stats |
| 10/25/2000 | UNC Asheville | Asheville, N.C. | W, 3-0 Recap | Stats |
| 10/29/2000 | Georgia Southern* | Statesboro, Ga. | W, 3-1 Recap | Stats |
| 11/02/2000 | Wofford* | Cullowhee, N.C. | W, 3-0 Recap | Stats |
| 11/04/2000 | Mercer | Cullowhee, N.C. | W, 3-0 Recap | Stats |
| 11/04/2000 | NC A&T | Cullowhee, N.C. | W, 3-0 Recap | Stats |
| 11/06/2000 | Furman* | Greenville, S.C. | L, 3-0 Recap | Stats |
| 11/08/2000 | Chattanooga* | Chattanooga, Tenn. | W, 3-2 Recap | Stats |
| 11/11/2000 | The Citadel* | Charleston, S.C. | W, 3-0 Recap | Stats |
| 11/12/2000 | College of Charleston* | Charleston, S.C. | W, 3-1 Recap | Stats |
| 11/17/2000 | Appalachian State | Charleston, S.C. | W, 3-2 Recap | Stats |
| 11/19/2000 | Davidson | Charleston, S.C. | L, 3-2 Recap | Stats |